{"id":231606,"date":"2022-07-18T12:03:29","date_gmt":"2022-07-18T12:03:29","guid":{"rendered":"https:\/\/equicord.com\/?page_id=231606"},"modified":"2022-11-29T14:10:00","modified_gmt":"2022-11-29T14:10:00","slug":"desarrollo-de-dogstem","status":"publish","type":"page","link":"https:\/\/equicord.com\/en\/desarrollo-de-dogstem\/","title":{"rendered":"Development"},"content":{"rendered":"

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Development<\/h1>\n

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Clinical results<\/h2>\n

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The results of the clinical trial are based on the study of the lameness in a plate-force platform as primary endpoint. This test allows us to evaluate the evolution of lameness objectively, comparing the weight that the animal carries on each limb and thus being able to assign a numerical value to the degree of lameness.<\/p>\n

The use of tools that make it possible to transform a typically subjective measure such as pain and lameness into a quantitative variable by force platform gives robustness to the results that have been rare until now.\n<\/p>\n

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DogStem does not seek only a partial improvement, but a substantial improvement in the quality of life and reduction of pain<\/h2>\n

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Lameness reduction<\/h3>\n

Preliminary results show that 63% of the dogs treated with DogStem improved their gait analysis<\/strong> en la plataforma de fuerza demostrando un menor grado de cojera y dolor articular, en cambio menos del 10% de los perros tratados con placebo mejoro su an\u00e1lisis de pisada.[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb custom_css_main_element_last_edited=\u00bbon|tablet\u00bb custom_css_main_element_tablet=\u00bbwidth: 50%;\u00bb custom_css_main_element_phone=\u00bbwidth: 50%;\u00bb][et_pb_circle_counter title=\u00bb\u00c9xito del grupo tratamiento\u00bb number=\u00bb63″ bar_bg_color=\u00bb#f5b71a\u00bb circle_color=\u00bbrgba(214,222,236,0.38)\u00bb circle_color_alpha=\u00bb1″ _builder_version=\u00bb4.17.6″ _module_preset=\u00bbdefault\u00bb title_font=\u00bb||||||||\u00bb title_text_color=\u00bb#ffffff\u00bb number_text_color=\u00bb#f5b71a\u00bb number_font_size=\u00bb3.5rem\u00bb background_layout=\u00bbdark\u00bb max_width=\u00bb210px\u00bb custom_margin_tablet=\u00bb\u00bb custom_margin_phone=\u00bb\u00bb custom_margin_last_edited=\u00bbon|tablet\u00bb custom_css_circle_counter_title=\u00bbtext-transform: uppercase;||letter-spacing: 2px;||font-size: 1em;||font-weight: 400;\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_circle_counter][\/et_pb_column][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb custom_css_main_element=\u00bbwidth: 50%;\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_circle_counter title=\u00bb\u00c9xito del grupo placebo\u00bb number=\u00bb8″ bar_bg_color=\u00bb#d6deec\u00bb circle_color=\u00bbrgba(214,222,236,0.38)\u00bb circle_color_alpha=\u00bb1″ _builder_version=\u00bb4.17.6″ _module_preset=\u00bbdefault\u00bb title_font=\u00bb||||||||\u00bb title_text_color=\u00bb#ffffff\u00bb number_text_color=\u00bb#d6deec\u00bb number_font_size=\u00bb3.5rem\u00bb background_layout=\u00bbdark\u00bb max_width=\u00bb210px\u00bb custom_css_circle_counter_title=\u00bbtext-transform: uppercase;||letter-spacing: 2px;||font-size: 1em;||font-weight: 400;\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_circle_counter][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00bb1″ custom_padding_last_edited=\u00bbon|phone\u00bb _builder_version=\u00bb4.17.6″ _module_preset=\u00bbdefault\u00bb background_enable_color=\u00bboff\u00bb use_background_color_gradient=\u00bbon\u00bb background_color_gradient_stops=\u00bb#ffffff 0%|#E9EEF5 100%\u00bb background_color_gradient_start=\u00bb#ffffff\u00bb background_color_gradient_end=\u00bb#E9EEF5″ custom_padding=\u00bb4vw||6vw||false|false\u00bb custom_padding_tablet=\u00bb8vw||6vw||false|false\u00bb custom_padding_phone=\u00bb12vw||||false|false\u00bb top_divider_color=\u00bb#E9EEF5″ top_divider_height=\u00bb4vw\u00bb top_divider_flip=\u00bbvertical\u00bb top_divider_height_tablet=\u00bb\u00bb top_divider_height_phone=\u00bb\u00bb top_divider_height_last_edited=\u00bbon|desktop\u00bb bottom_divider_color=\u00bb#262626″ bottom_divider_height=\u00bb2vw\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_row column_structure=\u00bb1_3,1_3,1_3″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_text _builder_version=\u00bb4.17.6″ _module_preset=\u00bbdefault\u00bb header_3_font_size=\u00bb1.6rem\u00bb custom_margin_tablet=\u00bb||2rem||false|false\u00bb custom_margin_phone=\u00bb\u00bb custom_margin_last_edited=\u00bbon|phone\u00bb text_font_size_tablet=\u00bb\u00bb text_font_size_phone=\u00bb\u00bb text_font_size_last_edited=\u00bbon|phone\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

Orthopedic Assessment<\/h3>\n

collaborating hospitals carry out an orthopedic evaluation at different times after the infiltration.<\/p>\n

In the orthopedic examination performed, 77% of the patients treated with stem cells\u00a0showed improvement in the infiltrated joint<\/strong>, frente a un efecto placebo del 46%.[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb custom_css_main_element=\u00bbwidth: 50%;\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_circle_counter title=\u00bb\u00c9xito del grupo tratamiento\u00bb number=\u00bb77″ bar_bg_color=\u00bb#f2ad00″ circle_color=\u00bbrgba(214,222,236,0.38)\u00bb circle_color_alpha=\u00bb1″ _builder_version=\u00bb4.17.6″ _module_preset=\u00bbdefault\u00bb title_font=\u00bb||||||||\u00bb title_text_color=\u00bb#24519b\u00bb number_text_color=\u00bb#f2ad00″ number_font_size=\u00bb3.5rem\u00bb background_layout=\u00bbdark\u00bb max_width=\u00bb210px\u00bb custom_margin_tablet=\u00bb\u00bb custom_margin_phone=\u00bb\u00bb custom_margin_last_edited=\u00bbon|tablet\u00bb custom_css_circle_counter_title=\u00bbtext-transform: uppercase;||letter-spacing: 2px;||font-size: 1em;||font-weight: 400;\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_circle_counter][\/et_pb_column][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb custom_css_main_element=\u00bbwidth: 50%;\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_circle_counter title=\u00bb\u00c9xito del grupo placebo\u00bb number=\u00bb46″ bar_bg_color=\u00bb#a9c5e0″ circle_color=\u00bbrgba(214,222,236,0.38)\u00bb circle_color_alpha=\u00bb1″ _builder_version=\u00bb4.17.6″ _module_preset=\u00bbdefault\u00bb title_font=\u00bb||||||||\u00bb title_text_color=\u00bb#24519b\u00bb number_text_color=\u00bb#a9c5e0″ number_font_size=\u00bb3.5rem\u00bb background_layout=\u00bbdark\u00bb max_width=\u00bb210px\u00bb custom_css_circle_counter_title=\u00bbtext-transform: uppercase;||letter-spacing: 2px;||font-size: 1em;||font-weight: 400;\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_circle_counter][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00bb1″ custom_padding_last_edited=\u00bbon|phone\u00bb _builder_version=\u00bb4.17.6″ _module_preset=\u00bbdefault\u00bb background_color=\u00bbrgba(0,0,0,0)\u00bb use_background_color_gradient=\u00bbon\u00bb background_color_gradient_direction=\u00bb126deg\u00bb background_color_gradient_stops=\u00bb#24519b 0%|#6eabd3 100%\u00bb background_color_gradient_start=\u00bb#24519b\u00bb background_color_gradient_end=\u00bb#6eabd3″ custom_padding=\u00bb7vw||2vw||false|false\u00bb custom_padding_tablet=\u00bb12vw||4vw||false|false\u00bb custom_padding_phone=\u00bb12vw||||false|false\u00bb top_divider_style=\u00bbarrow\u00bb top_divider_color=\u00bb#E9EEF5″ top_divider_height=\u00bb3vw\u00bb top_divider_height_tablet=\u00bb6vw\u00bb top_divider_height_phone=\u00bb\u00bb top_divider_height_last_edited=\u00bbon|phone\u00bb bottom_divider_style=\u00bbarrow\u00bb bottom_divider_color=\u00bb#ffffff\u00bb bottom_divider_height=\u00bb3vw\u00bb bottom_divider_height_tablet=\u00bb6vw\u00bb bottom_divider_height_phone=\u00bb\u00bb bottom_divider_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_row column_structure=\u00bb1_3,1_3,1_3″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_text _builder_version=\u00bb4.17.6″ _module_preset=\u00bbdefault\u00bb text_font=\u00bb||||||||\u00bb text_text_color=\u00bb#d6deec\u00bb header_3_font_size=\u00bb1.6rem\u00bb background_layout=\u00bbdark\u00bb custom_margin_tablet=\u00bb||2rem||false|false\u00bb custom_margin_phone=\u00bb\u00bb custom_margin_last_edited=\u00bbon|desktop\u00bb text_font_size_tablet=\u00bb\u00bb text_font_size_phone=\u00bb\u00bb text_font_size_last_edited=\u00bbon|desktop\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

Improvement of quality of life<\/h3>\n

According owners opinion, 65% of dogs treated with DogStem substantially improved their quality of life after treatment, while only 19% of dogs treated with placebo saw improvement.<\/p>\n

La mejora de la calidad de vida fue evaluada por los propietarios en actividades de la vida cotidiana de nuestras mascotas como pasear, jugar con otros perros, subirse al sof\u00e1, subir escaleras, etc.[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb custom_css_main_element_last_edited=\u00bbon|tablet\u00bb custom_css_main_element_tablet=\u00bbwidth: 50%;\u00bb custom_css_main_element_phone=\u00bbwidth: 50%;\u00bb][et_pb_circle_counter title=\u00bb\u00c9xito del grupo tratamiento\u00bb number=\u00bb65″ bar_bg_color=\u00bb#f5b71a\u00bb circle_color=\u00bbrgba(214,222,236,0.38)\u00bb circle_color_alpha=\u00bb1″ _builder_version=\u00bb4.17.6″ _module_preset=\u00bbdefault\u00bb title_font=\u00bb||||||||\u00bb title_text_color=\u00bb#ffffff\u00bb number_text_color=\u00bb#f5b71a\u00bb number_font_size=\u00bb3.5rem\u00bb background_layout=\u00bbdark\u00bb max_width=\u00bb210px\u00bb custom_margin_tablet=\u00bb\u00bb custom_margin_phone=\u00bb\u00bb custom_margin_last_edited=\u00bbon|tablet\u00bb custom_css_circle_counter_title=\u00bbtext-transform: uppercase;||letter-spacing: 2px;||font-size: 1em;||font-weight: 400;\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_circle_counter][\/et_pb_column][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb custom_css_main_element=\u00bbwidth: 50%;\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_circle_counter title=\u00bb\u00c9xito del grupo placebo\u00bb number=\u00bb13″ bar_bg_color=\u00bb#d6deec\u00bb circle_color=\u00bbrgba(214,222,236,0.38)\u00bb circle_color_alpha=\u00bb1″ _builder_version=\u00bb4.17.6″ _module_preset=\u00bbdefault\u00bb title_font=\u00bb||||||||\u00bb title_text_color=\u00bb#ffffff\u00bb number_text_color=\u00bb#d6deec\u00bb number_font_size=\u00bb3.5rem\u00bb background_layout=\u00bbdark\u00bb max_width=\u00bb210px\u00bb custom_css_circle_counter_title=\u00bbtext-transform: uppercase;||letter-spacing: 2px;||font-size: 1em;||font-weight: 400;\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_circle_counter][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00bb1″ custom_padding_last_edited=\u00bbon|phone\u00bb _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb custom_padding=\u00bb5rem||5rem||false|false\u00bb custom_padding_tablet=\u00bb4rem||||false|false\u00bb custom_padding_phone=\u00bb\u00bb bottom_divider_style=\u00bbcurve\u00bb bottom_divider_color=\u00bb#262626″ bottom_divider_height=\u00bb2vw\u00bb bottom_divider_height_tablet=\u00bb3vw\u00bb bottom_divider_height_phone=\u00bb\u00bb bottom_divider_height_last_edited=\u00bbon|desktop\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb bottom_divider_height__hover_enabled=\u00bboff|desktop\u00bb][et_pb_row _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb custom_margin=\u00bb3vw||||false|false\u00bb custom_margin_tablet=\u00bb\u00bb custom_margin_phone=\u00bb\u00bb custom_margin_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_text _builder_version=\u00bb4.19.1″ _module_preset=\u00bbdefault\u00bb header_2_font=\u00bb||||||||\u00bb header_2_font_size=\u00bb3em\u00bb header_4_font=\u00bb||||||||\u00bb hover_enabled=\u00bb0″ header_2_font_size_tablet=\u00bb2.5em\u00bb header_2_font_size_phone=\u00bb2.2em\u00bb header_2_font_size_last_edited=\u00bbon|desktop\u00bb header_4_text_color_tablet=\u00bb\u00bb header_4_text_color_phone=\u00bb\u00bb header_4_text_color_last_edited=\u00bbon|desktop\u00bb header_4_font_size_tablet=\u00bb\u00bb header_4_font_size_phone=\u00bb\u00bb header_4_font_size_last_edited=\u00bbon|desktop\u00bb global_colors_info=\u00bb{}\u00bb sticky_enabled=\u00bb0″]<\/p>\n

Clinical development<\/h2>\n

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Preclinical<\/h3>\n

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Preclinical 100%<\/p>\n

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Collection of safety and efficacy data in the intra-articular use of autologous mesenchymal stem cells in dogs with Osteoarthritis<\/p>\n

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Phase I<\/h3>\n

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Safety 100%<\/p>\n

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Single and repeated dose<\/p>\n

*VICH GL9<\/strong><\/p>\n

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Immunogenicity clinical trial: Cellular and Humoral response<\/p>\n

*VICH GL9<\/strong><\/p>\n

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Phase II<\/h3>\n

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Exploratory 100%<\/p>\n

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Exploratory study<\/strong> of safety and efficacy in canine osteoarthritis (OA) treated with mesenchymal stem cells versus placebo in pilot animals<\/p>\n

*VICH GL9<\/strong><\/p>\n

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Phase III<\/h3>\n

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Confirmatory 100%<\/p>\n

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Confirmatory clinical trial of safety and efficacy in the use of DogStem in dogs with mild to severe osteoarthritis (OA) under field conditions<\/p>\n

*VICH GL9<\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"

DogStem DesarrolloResultados cl\u00ednicosLos resultados del ensayo cl\u00ednico se basan en el estudio de la pisada en plataforma de fuerza como variable primaria. Esta prueba nos permite evaluar la evoluci\u00f3n de la cojera de manera objetiva, comparando el peso que el animal carga sobre cada extremidad y pudiendo as\u00ed, asignarle un valor num\u00e9rico al grado de […]<\/p>","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false},"_links":{"self":[{"href":"https:\/\/equicord.com\/en\/wp-json\/wp\/v2\/pages\/231606"}],"collection":[{"href":"https:\/\/equicord.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/equicord.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/equicord.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/equicord.com\/en\/wp-json\/wp\/v2\/comments?post=231606"}],"version-history":[{"count":7,"href":"https:\/\/equicord.com\/en\/wp-json\/wp\/v2\/pages\/231606\/revisions"}],"predecessor-version":[{"id":231727,"href":"https:\/\/equicord.com\/en\/wp-json\/wp\/v2\/pages\/231606\/revisions\/231727"}],"wp:attachment":[{"href":"https:\/\/equicord.com\/en\/wp-json\/wp\/v2\/media?parent=231606"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}