{ "id": 231657, "date": "2022-07-26T16:37:56", "date_gmt": "2022-07-26T16:37:56", "guid": { "rendered": "https:\/\/equicord.com\/?page_id=231657" }, "modified": "2022-07-26T17:05:28", "modified_gmt": "2022-07-26T17:05:28", "slug": "desarrollo-de-horstem", "status": "publish", "type": "page", "link": "https:\/\/equicord.com\/es\/desarrollo-de-horstem\/", "title": { "rendered": "Desarrollo de HorStem" }, "content": { "rendered": "

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Desarrollo<\/h1>\n

EquiCord ha llevado a cabo un exhaustivo proceso de investigaci\u00f3n y desarrollo para demostrar la calidad, seguridad y eficacia de las c\u00e9lulas madre de cord\u00f3n umbilical.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00bb1″ custom_padding_last_edited=\u00bbon|desktop\u00bb _builder_version=\u00bb4.17.6″ _module_preset=\u00bbdefault\u00bb background_enable_color=\u00bboff\u00bb use_background_color_gradient=\u00bbon\u00bb background_color_gradient_direction=\u00bb0deg\u00bb background_color_gradient_stops=\u00bbrgba(36,81,155,0.13) 0%|rgba(36,81,155,0) 100%\u00bb background_color_gradient_start=\u00bbrgba(36,81,155,0.22)\u00bb background_color_gradient_end=\u00bbrgba(36,81,155,0.12)\u00bb custom_padding=\u00bb||6vw||false|false\u00bb custom_padding_tablet=\u00bb||8vw||false|false\u00bb custom_padding_phone=\u00bb||6vw||false|false\u00bb top_divider_color=\u00bb#ffffff\u00bb top_divider_height=\u00bb3vw\u00bb top_divider_flip=\u00bbhorizontal\u00bb bottom_divider_color=\u00bb#262626″ bottom_divider_height=\u00bb2vw\u00bb bottom_divider_flip=\u00bbhorizontal\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_row _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb custom_margin=\u00bb3vw||||false|false\u00bb custom_margin_tablet=\u00bb\u00bb custom_margin_phone=\u00bb\u00bb custom_margin_last_edited=\u00bbon|phone\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb header_2_font=\u00bb||||||||\u00bb header_2_font_size=\u00bb3em\u00bb header_4_font=\u00bb||||||||\u00bb header_2_font_size_tablet=\u00bb2.5em\u00bb header_2_font_size_phone=\u00bb2.2em\u00bb header_2_font_size_last_edited=\u00bbon|desktop\u00bb header_4_text_color_tablet=\u00bb\u00bb header_4_text_color_phone=\u00bb\u00bb header_4_text_color_last_edited=\u00bbon|desktop\u00bb header_4_font_size_tablet=\u00bb\u00bb header_4_font_size_phone=\u00bb\u00bb header_4_font_size_last_edited=\u00bbon|desktop\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

Desarrollo cl\u00ednico<\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00bb2_5,3_5″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb custom_margin_tablet=\u00bb\u00bb custom_margin_phone=\u00bb\u00bb custom_margin_last_edited=\u00bbon|phone\u00bb custom_padding=\u00bb0px||||false|false\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb2_5″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb header_3_font_size=\u00bb44px\u00bb global_colors_info=\u00bb{}\u00bb]La autorizaci\u00f3n de un producto como medicamento veterinario requiere de la realizaci\u00f3n de diversos ensayos cl\u00ednicos con el fin de garantizar la seguridad y eficacia del medicamento.[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb3_5″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb text_font=\u00bb||||||||\u00bb text_text_color=\u00bb#24519b\u00bb text_font_size=\u00bb1.5em\u00bb text_line_height=\u00bb1.6rem\u00bb header_4_font_size=\u00bb22px\u00bb custom_padding_tablet=\u00bb\u00bb custom_padding_phone=\u00bb\u00bb custom_padding_last_edited=\u00bbon|phone\u00bb custom_css_main_element=\u00bbfont-weight: 500;\u00bb global_colors_info=\u00bb{}\u00bb]En EquiCord hemos llevado a cabo 7 ensayos cl\u00ednicos para la autorizaci\u00f3n de comercializaci\u00f3n y actualmente estamos desarrollando 3 ensayos m\u00e1s.[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb custom_margin=\u00bb2rem||||false|false\u00bb custom_padding=\u00bb||12px|||\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_text module_class=\u00bblemon\u00bb _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb header_3_font_size=\u00bb1.8em\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

Seguridad y eficacia de las MSC en OA equina<\/h3>\n

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Precl\u00ednico<\/h3>\n

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Prueba de concepto:<\/p>\n

Seguridad<\/strong> del uso alog\u00e9nico intraarticular de c\u00e9lulas madre mesenquimales de cord\u00f3n umbilical equino en caballos sanos<\/p>\n

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Fase I<\/h3>\n

[\/et_pb_text][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#123163″ text_font_size=\u00bb0.8rem\u00bb text_line_height=\u00bb1.2rem\u00bb background_color=\u00bbrgba(0,0,0,0)\u00bb custom_margin=\u00bb0px||3px||false|false\u00bb custom_padding=\u00bb15px|15px|15px|15px|true|true\u00bb border_width_bottom=\u00bb2px\u00bb border_color_bottom=\u00bb#96a7ce\u00bb border_style_bottom=\u00bbdashed\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

Estudio de Seguridad en especie de destino: Dosis \u00fanica y dosis repetida<\/strong>\u00a0<\/strong><\/p>\n

*VICH GL9<\/strong><\/p>\n

[\/et_pb_text][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#123163″ text_font_size=\u00bb0.8rem\u00bb text_line_height=\u00bb1.2rem\u00bb background_color=\u00bbrgba(0,0,0,0)\u00bb custom_margin=\u00bb0px||3px||false|false\u00bb custom_padding=\u00bb15px|15px|15px|15px|true|true\u00bb border_width_bottom=\u00bb2px\u00bb border_color_bottom=\u00bb#96a7ce\u00bb border_style_bottom=\u00bbdashed\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

Ensayo cl\u00ednico\u00a0 Inmunogenicidad<\/strong>: respuesta Celular y Humoral<\/p>\n

*VICH GL9<\/strong><\/p>\n

[\/et_pb_text][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#123163″ text_font_size=\u00bb0.8rem\u00bb text_line_height=\u00bb1.2rem\u00bb background_color=\u00bbrgba(0,0,0,0)\u00bb custom_margin=\u00bb0px||3px||false|false\u00bb custom_padding=\u00bb15px|15px|15px|15px|true|true\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

Estudio Cl\u00ednico sobre Tumorogenesis<\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_5″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb background_color=\u00bb#ffffff\u00bb border_radii=\u00bboff|15px|5px|15px|5px\u00bb border_radii_tablet=\u00bb\u00bb border_radii_phone=\u00bboff|10px||10px|\u00bb border_radii_last_edited=\u00bbon|phone\u00bb box_shadow_style=\u00bbpreset3″ box_shadow_vertical=\u00bb26px\u00bb box_shadow_blur=\u00bb25px\u00bb box_shadow_spread=\u00bb-16px\u00bb box_shadow_color=\u00bbrgba(36,81,155,0.25)\u00bb global_colors_info=\u00bb{}\u00bb border_radii__hover_enabled=\u00bboff|desktop\u00bb][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#ffffff\u00bb header_3_font=\u00bb||||||||\u00bb header_3_text_color=\u00bb#ffffff\u00bb header_3_font_size=\u00bb1.2em\u00bb background_color=\u00bb#24519b\u00bb custom_margin=\u00bb0px||0px||false|false\u00bb custom_padding=\u00bb1em|0.5em|0.4em|1.3em|false|false\u00bb border_radii=\u00bboff||||\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

Fase II<\/h3>\n

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Prueba de concepto: Investigaci\u00f3n de seguridad y eficacia<\/strong> en la administraci\u00f3n intraarticular a la dosis seleccionada de c\u00e9lulas madre alog\u00e9nicas de cord\u00f3n umbilical en caballos con enfermedad degenerativa articular<\/p>\n

*VICH GL9<\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_5″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb background_color=\u00bb#ffffff\u00bb border_radii=\u00bboff|15px|5px|15px|5px\u00bb border_radii_tablet=\u00bb\u00bb border_radii_phone=\u00bboff|10px||10px|\u00bb border_radii_last_edited=\u00bbon|phone\u00bb box_shadow_style=\u00bbpreset3″ box_shadow_vertical=\u00bb26px\u00bb box_shadow_blur=\u00bb25px\u00bb box_shadow_spread=\u00bb-16px\u00bb box_shadow_color=\u00bbrgba(36,81,155,0.25)\u00bb global_colors_info=\u00bb{}\u00bb border_radii__hover_enabled=\u00bboff|desktop\u00bb][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#ffffff\u00bb header_3_font=\u00bb||||||||\u00bb header_3_text_color=\u00bb#ffffff\u00bb header_3_font_size=\u00bb1.2em\u00bb background_color=\u00bb#24519b\u00bb custom_margin=\u00bb0px||0px||false|false\u00bb custom_padding=\u00bb1em|0.5em|0.4em|1.3em|false|false\u00bb border_radii=\u00bboff||||\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

Fase III<\/h3>\n

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Derterminaci\u00f3n de la seguridad y la eficacia <\/strong>de las EUC-MSC en el tratamiento sintom\u00e1tico asociado a Enfermedad degenerativa articular (Ostreoartrosis) en caballos en condiciones de campo<\/p>\n

*VICH GL9<\/strong><\/p>\n

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Confirmaci\u00f3n de la seguridad y eficacia <\/strong>en la administraci\u00f3n intraarticular de c\u00e9lulas madre mesenquimales alog\u00e9nicas de cord\u00f3n umbilical en caballos con enfermedad degenerativa<\/p>\n

*VICH GL9<\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_5″ _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb background_color=\u00bb#ffffff\u00bb border_radii=\u00bboff|15px|5px|15px|5px\u00bb border_radii_tablet=\u00bb\u00bb border_radii_phone=\u00bboff|10px||10px|\u00bb border_radii_last_edited=\u00bbon|phone\u00bb box_shadow_style=\u00bbpreset3″ box_shadow_vertical=\u00bb26px\u00bb box_shadow_blur=\u00bb25px\u00bb box_shadow_spread=\u00bb-16px\u00bb box_shadow_color=\u00bbrgba(36,81,155,0.25)\u00bb global_colors_info=\u00bb{}\u00bb border_radii__hover_enabled=\u00bboff|desktop\u00bb][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#ffffff\u00bb header_3_font=\u00bb||||||||\u00bb header_3_text_color=\u00bb#ffffff\u00bb header_3_font_size=\u00bb1.2em\u00bb background_color=\u00bb#24519b\u00bb custom_margin=\u00bb0px||0px||false|false\u00bb custom_padding=\u00bb1em|0.5em|0.4em|1.3em|false|false\u00bb border_radii=\u00bboff||||\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

Fase IV<\/h3>\n

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Estudio de seguridad y eficacia a largo plazo<\/strong>: estudio de seguimiento de dos a\u00f1os de seguridad y eficacia<\/p>\n

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Estudio encuesta postcomercializaci\u00f3n\u00a0 <\/strong>en 800 caballos sobre la seguridad y la eficacia de HorStem<\/p>\n

 <\/p>\n

*VICH GL9<\/strong><\/p>\n

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Resultados cl\u00ednicos<\/h2>\n

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Los ensayos cl\u00ednicos dise\u00f1ados y llevados a cabo por nuestro equipo cient\u00edfico han demostrado que HorStem es eficaz en la reducci\u00f3n de la cojera en caballos con enfermedad degenerativa articular de leve a moderada.<\/p>\n

Todos nuestros ensayos cl\u00ednicos han sido realizados siguiendo las normativas internacionales de homogenizaci\u00f3n de ensayos cl\u00ednicos VICH GL9 y tras la autorizaci\u00f3n de la Agencia Espa\u00f1ola del Medicamento y Productos Sanitarios (AEMPS).<\/p>\n

[\/et_pb_text][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#ffffff\u00bb text_font_size=\u00bb1.6em\u00bb text_line_height=\u00bb1.3em\u00bb custom_margin=\u00bb||5px||false|false\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

El 72% de los caballos tratados redujeron su grado de cojera a ausencia de cojera o cojera inconsistente<\/p>\n

[\/et_pb_text][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#ffffff\u00bb text_font_size=\u00bb0.95em\u00bb text_line_height=\u00bb1.5em\u00bb global_colors_info=\u00bb{}\u00bb](\u2264 grado 1 acorde a la Escala Americana de Veterinarios Especialistas en \u00c9quidos).[\/et_pb_text][et_pb_text _builder_version=\u00bb4.16″ _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#a9c5e0″ global_colors_info=\u00bb{}\u00bb]<\/p>\n

As\u00ed mismo, estudios a largo plazo han demostrado que la eficacia de HorStem es muy duradera, demostr\u00e1ndose que el 83% de los animales no recayeron en sus s\u00edntomas ni necesitaron medicaci\u00f3n adicional 12 meses despu\u00e9s de la aplicaci\u00f3n de HorStem.<\/strong><\/p>\n

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Horstem Desarrollo EquiCord ha llevado a cabo un exhaustivo proceso de investigaci\u00f3n y desarrollo para demostrar la calidad, seguridad y eficacia de las c\u00e9lulas madre de cord\u00f3n umbilical.Desarrollo cl\u00ednicoLa autorizaci\u00f3n de un producto como medicamento veterinario requiere de la realizaci\u00f3n de diversos ensayos cl\u00ednicos con el fin de garantizar la seguridad y eficacia del medicamento.En […]<\/p>", "protected": false }, "author": 2, "featured_media": 0, "parent": 0, "menu_order": 0, "comment_status": "closed", "ping_status": "closed", "template": "", "meta": { "_et_pb_use_builder": "on", "_et_pb_old_content": "", "_et_gb_content_width": "", "inline_featured_image": false }, "_links": { "self": [ { "href": "https:\/\/equicord.com\/es\/wp-json\/wp\/v2\/pages\/231657" } ], "collection": [ { "href": "https:\/\/equicord.com\/es\/wp-json\/wp\/v2\/pages" } ], "about": [ { "href": "https:\/\/equicord.com\/es\/wp-json\/wp\/v2\/types\/page" } ], "author": [ { "embeddable": true, "href": "https:\/\/equicord.com\/es\/wp-json\/wp\/v2\/users\/2" } ], "replies": [ { "embeddable": true, "href": "https:\/\/equicord.com\/es\/wp-json\/wp\/v2\/comments?post=231657" } ], "version-history": [ { "count": 6, "href": "https:\/\/equicord.com\/es\/wp-json\/wp\/v2\/pages\/231657\/revisions" } ], "predecessor-version": [ { "id": 231679, "href": "https:\/\/equicord.com\/es\/wp-json\/wp\/v2\/pages\/231657\/revisions\/231679" } ], "wp:attachment": [ { "href": "https:\/\/equicord.com\/es\/wp-json\/wp\/v2\/media?parent=231657" } ], "curies": [ { "name": "wp", "href": "https:\/\/api.w.org\/{rel}", "templated": true } ] } }