DogStem
The results of the clinical trial are based on the study of gait analysis on a force platform as the primary variable. This test allows us to objectively evaluate the progression of lameness by comparing the weight the animal bears on each limb and thus assigning a numerical value to the degree of lameness.
The use of tools that allow transforming a typically subjective measure such as pain and lameness into a quantitative variable by force platform gives a robustness to the results that is uncommon until now.
Preliminary results show that 63% of dogs treated with DogStem improved their gait analysis on the force platform, demonstrating a lower degree of lameness and joint pain, whereas less than 10% of dogs treated with placebo improved their gait analysis.
In addition to the objective force platform assessment, specialist traumatologists from our collaborating hospitals perform an orthopedic evaluation at different times after the infiltration.
In the orthopedic examination performed, 77% of patients treated with stem cells showed improvement in the infiltrated joint, compared to a placebo effect of 46%.
According to the owners' opinion, 65% of the dogs treated with DogStem substantially improved their quality of life after treatment, while only 19% of the dogs treated with placebo saw improvement.
The improvement in quality of life was assessed by owners in everyday activities of our pets such as walking, playing with other dogs, getting on the sofa, climbing stairs, etc.
100% Preclinical
Collection of safety and efficacy data on the intra-articular use of autologous mesenchymal stem cells in dogs with osteoarthritis
100% Security
Safety study in target species: Single dose and repeated dose
*VICH GL9
Clinical trial Immunogenicity: Cellular and Humoral response
*VICH GL9
Exploratorio 100%
Exploratory study of the safety and efficacy of mesenchymal stem cells versus placebo in pilot animals in canine osteoarthritis (OA)
*VICH GL9
100% Confirmed
Confirmatory clinical trial of the safety and efficacy of DogStem in dogs with mild to severe osteoarthritis (OA) under field conditions
*VICH GL9